ADVERTISEMENT

1. Cowboys 52, Bills 17. Super Bowl XXVII. Jan. 31, 1994. Rose Bowl. Humiliation.

2. Redskins 37, Bills 24. Super Bowl XXVI. Jan. 26, 1993. Metrodome. Embarrassment.

3. Giants 20, Bills 19. Super Bowl XXV. Jan. 27, 1991. Tampa Stadium. Great game, but Bills should have won.

4. Cowboys 30, Bills 13. Super Bowl XXVIII. Jan. 30, 1994. Georgia Dome. Had Cowboys on ropes, collapsed.

5. Titans 22, Bills 16. Wild-card playoff. Jan. 8, 2000. Adelphia Coliseum. Music City Miracle.

6. Jaguars 30, Bills 27. Wild-card playoff. Dec. 28, 1996. Ralph Wilson Stadium. Kelly’s last game.

7. Patriots 56, Bills 10. Nov. 18, 2007. Ralph Wilson Stadium. Unbeaten Pats hand Bills most lopsided loss in team history.

8. Bengals 28, Bills 21. Divisional playoff. Jan. 3, 1982. Riverfront Stadium. Fergy lets clock run out on key play of potential game-tying drive.

9. Chargers 20, Bills 14. Divisional playoff. Jan. 3, 1981. San Diego Stadium. A 50-yard Dan Fouts TD pass with 2:08 left beats valiant Bills.

10. Steelers 29, Bills 24. Jan. 2, 2005. Ralph Wilson Stadium. Pittsburgh subs snatch playoff berth from Bills’ mouths.

11. Browns 34, Bills 30. Divisional playoff. Jan. 6 1990. Cleveland Stadium. Ronnie Harmon drops potential winning-TD pass in end zone to thwart Bills comeback.

12. Chiefs 31, Bills 7. AFL Championship. Jan. 1, 1967. War Memorial Stadium. Chiefs earn trip to Super Bowl I. Chiefs clearly were the superior team.

14. Dolphins 31, Bills 21. Dec. 7, 1975. Orange Bowl. Trailing by three, referee Gene Barth overrules a Bills fumble recovery deep in Miami territory, then Pat Toomay is penalized for brushing linesman Jerry Bergman. Bills lose 12th straight to Fish.

15. Cowboys 25, Bills 24. Oct. 8, 2007. Ralph Wilson Stadium. Bills get two INT returns for TDs, a kickoff return for a TD and win the turnover battle, 6-1, but give up 10 points in the last 30 seconds to lose before a frantic Monday night crowd.

16. Raiders 48, Bills 6. Sept. 15, 1968. War Memorial Stadium. George Atkinson sets AFL record with 205 punt return yards and Bills finish with minus-19 passing yards. Coach Joe Collier is fired after the game.

17. Seahawks 56, Bills 17. Oct. 30, 1977. Kingdome. Seahawks gain 559 yards in O.J. Simpson’s last game as a Bill.

18. Browns 6, Bills 3. Oct. 11, 2009. Ralph Wilson Stadium. Bills lose despite holding Browns QB Derek Anderson to 2 of 17 passing for 23 yards. Buffalo makes nine false starts and manages only a field goal against 32nd-ranked defense.

19. Dolphins 35, Bills 30. Oct. 26, 1975. Rich Stadium. Clinging to a two-point lead, Joe Ferguson throws interception to Jake Scott at Buffalo 22 with 3:04 left.

20. Colts 58, Bills 20. Dec. 12, 1976. Baltimore’s Memorial Stadium. The most points allowed in Bills history and the worst run-for-the-bus finale in team history.