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A new federal report blames a combination of problems for a mysterious and dramatic disappearance of U.S. honeybees since 2006.

The intertwined factors cited include a parasitic mite, multiple viruses, bacteria, poor nutrition, genetics, habitat loss and pesticides.

The multiple causes make it harder to do something about what’s called colony collapse disorder, experts say. The disorder has caused as much as one-third of the nation’s bees to just disappear each winter since 2006.

Bees, especially honeybees, are needed to pollinate crops.

The federal report, issued by the Agriculture Department and the Environmental Protection Agency, said the biggest culprit is the parasitic mite varroa destructor, calling it “the single most detrimental pest of honeybees.”

The problem has also hit bee colonies in Europe, where regulators are considering a ban on a type of pesticides known as neonicotinoids that some environmental groups blame for the bee collapse. The U.S. report cites pesticides, but near the bottom of the list of factors. And federal officials and researchers advising them said the science doesn’t justify a ban of the pesticides yet.

May Berenbaum, a top bee researcher from the University of Illinois, said in an interview that she was “extremely dubious” that banning the pesticide would have any effect on bee health. She participated in a large conference of scientists that the government brought together last year to figure out what’s going on, and the new report is the result of that conference.

Berenbaum said more than 100 different chemicals – not just the pesticides that may be banned in Europe – have been found in bee colonies. Scientists find it hard to calculate how they react in different dosages and at different combinations.

Some of these chemicals harm the immune systems of bees or amplify viruses, said Penn State University bee expert Diana Cox-Foster.

Sonny Ramaswamy, a top U.S. Department of Agriculture official, said the scientific consensus is that there are multiple factors “and you can’t parse any one out to be the smoking gun.”

USDA bee researcher Jeff Pettis also cited modern farming practices that often leave little forage area for bees.

Dave Gaulson of the University of Stirling in Scotland, who conducted a study last year that implicated the chemical, said he can’t disagree with the overall conclusions of the U.S. government report. However, he said it could have emphasized pesticides more.

Pollinators like honeybees are crucial to the U.S. food supply. About $30 billion a year in agriculture depends on their health, said Ramaswamy.

Besides making honey, honeybees pollinate more than 90 flowering crops. Among them are a variety of fruits and vegetables: apples, nuts, avocados, soybeans, asparagus, broccoli, citrus fruit and cranberries. About one-third of the human diet comes from insect-pollinated plants, and the honeybee is responsible for 80 percent of that pollination.

Zac Browning, a fourth-generation commercial beekeeper who has hives in Idaho, North Dakota and California, said the nation is “on the brink” of not having enough bees to pollinate its crops.

University of Maryland entomologist David Inouye, who was not part of the federal report, said he agrees that there are multiple causes.

“It’s not a simple situation. If it were one factor we would have identified it by now,” he said.

Berenbaum said there’s no single solution to the U.S. bee problem: “We’re not really well equipped or even used to fighting on multiple fronts.”