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The American Red Cross Serving Erie & Niagara Counties will open its headquarters in the Clement Mansion, 786 Delaware Ave., for tours this weekend to celebrate the building’s 100th anniversary.

Guided tours will be offered every 20 minutes from noon to 4 p.m. Saturday and Sunday for a suggested donation of $5.

Architect and family historian Peter W. Clement, whose great-grandparents built the E.B. Green-designed mansion, will talk about his family and the building at 10 a.m. Saturday, followed by a tour of the mansion.

Behind the Scenes Cocktail Tours, including beverages and hors d’oeuvres, will be offered from 6 to 8 p.m. Saturday. Tickets are $45. Reservations are requested for the Peter Clement lecture and the Cocktail Tours. Call 878-2396.