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CHICAGO (AP) Charlie Trotter had built a reputation so stellar that the culinary world still had high expectations for the famed chef after he closed his award-winning namesake Chicago restaurant last summer.

Trotter changed the way Americans viewed fine dining, and his restaurant put Chicago at the vanguard of the food world.

Trotter, 54, died Tuesday at a Chicago hospital after paramedics found him unresponsive at his home. An autopsy on Wednesday found no signs of foul play or trauma, but the Cook County Medical Examiner's Office said it may be as long as two months before a cause of death can be determined.

Fellow celebrity chef Rick Bayless said it's sad the world will never get to see what Trotter would do next.

"I knew that we would hear something more from him and I had hoped that we would have the chance to see the next chapter in his life," said Bayless, among a slew of well-known chefs who paid tribute to Trotter after learning of his death.

The Cook County Medical Examiner's Office did not say anything about whether the acclaimed chef's death was related to what friends and co-workers described as Trotter's declining health in recent years, or the seizure that one said he was hospitalized for over the summer. In a short news release, the office said that "additional tests, including a toxicology analysis will be conducted."

For decades, Trotter's name was synonymous with cutting-edge cuisine. He earned 10 James Beard Awards, wrote 10 cookbooks and in 1999 hosted his own public television series, "The Kitchen Sessions with Charlie Trotter."

Trotter's wife, Rochelle, said in a statement that his "impact upon American cuisine and the culinary world at large will always be remembered."

His restaurant was credited with training dozens of the nation's top chefs, including Grant Achatz and Graham Elliot.

"It was the beginning of the notion that America could have a real haute cuisine on par with Europe," said Anthony Bourdain, the best-selling author and chef who hosts the Travel Channel's "No Reservations." ''That was what Charlie did."

Yet Trotter never went to culinary school. He grew up in the northern Chicago suburb of Wilmette and majored in political science at the University of Wisconsin, Madison. But an inspiring meal several years earlier had planted the desire to cook.

After graduation, he created a de facto apprenticeship, landing his first job at a restaurant in Chicago's North Shore area called Sinclair's, where he worked under now well-known chefs such as Van Aken and Carrie Nahabedian.

From there Trotter moved to restaurants in Florida, San Francisco and France, all the while eating widely and reading cookbooks voraciously. When he returned to the U.S. and with financial backing from his family he purchased a Victorian house in Chicago and opened Charlie Trotter's there in 1987.

Trotter's food was grounded in classical French technique, but blended seamlessly with Asian influences. He believed fervently in the power of simplicity and clean cooking, turning to simple vegetable purees and stocks rather than heavy sauces to deliver standup flavor in menus that changed daily.

He also was an early advocate of using seasonal and organic ingredients, as well as sustainably raised or caught meat and seafood.

"Charlie was a visionary, an unbelievable chef that brought American cuisine to new heights," Emeril Lagasse, a close friend of Trotter's, said in an email. "We have lost a tremendous human being and an incredible chef and restaurateur."

Trotter was gruff, exacting, demanding and a culinary genius. And for years his restaurant was considered one of the best in the nation, earning two Michelin stars the first year the guide rated Chicago restaurants.

He also was giving. He created a charitable group that not only awarded culinary scholarships, but also brought disadvantaged children to his restaurant every week to teach them about fine dining.

But in time, the food world caught up with him. And food culture changed, with celebrity often trumping skill. It was a world to which he adapted poorly.

"The last few times I saw him were at food and wine festivals where people didn't recognize him. People did not acknowledge him for his incredibly important place in history," said Bourdain. "Back in Charlie's day, it was really the merit system. Being a great chef was enough. You didn't have to be lovable."

Meanwhile, chefs such as Achatz of award-winning Chicago restaurants Alinea and Next became so avant-garde, Trotter's menus seemed almost dated. And the very organic and seasonal philosophies he'd spearheaded had become commonplace.

In August 2012 and in keeping with his reputation for bold, unexpected moves Trotter closed his iconic 120-seat restaurant. His plan? Return to college to study philosophy.

"The one thing it will do for me is let me wipe a certain slate clean. And while I'm studying and reading and applying myself to something else, if I decide to come back to the restaurant world, I think I'm going to bring a different perspective," he told The Associated Press in an interview last year.

"My hope is to really learn how to think very differently on the whole thing," he said.

Larry Stone, a longtime friend and sommelier who worked with Trotter, said the chef was determined to remain active despite health issues, even though doctors had advised him a few years ago not to fly or exert himself. Close family friend and early Trotter mentor Norman Van Aken said Trotter was hospitalized in New York this summer after having a seizure, but he didn't know if that was related to his death.

Stone said Trotter didn't like the idea of closing the restaurant, but "it was taking a toll."

"He needed to release himself from the restaurant and take a break," Stone said. "We were all concerned about him."

Van Aken said it was a shame the public rarely saw other sides of Trotter's personality the wit that drove him to share video clips of W.C. Fields, his reenactments of scenes from "The Godfather," his love of Miles Davis.

Some might have thought the move from the restaurant world was too risky. Not Trotter.

"What's the worst that could happen? Life's too short. You may be on this planet for 80 years at best or who knows, but you can't just pedal around and do the same thing forever," he told the AP in 2012.

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AP Food Editor J.M. Hirsch is based in Concord, N.H. Associated Press writer Don Babwin in Chicago contributed to this report.