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By Milt Northrop

When two for-certain future Hall of Fame quarterbacks hook up in a National Football League game, it’s an intriguing event.

Most of the attention in an otherwise mundane Week Eight schedule in the NFL today will be directed towards tonight’s game between the New Orleans Saints and the Broncos in Denver and quarterbacks Drew Brees and Peyton Manning.

Two of the most productive passers in NFL history – Brees of the Saints and Manning of the Broncos – will go at it in the Mile High City. Their career accomplishments are already piled a mile high, figuratively.

Last week in a 35-28 win over Tampa Bay, Brees passed for four touchdowns, adding to his NFL record of 49 straight games with a scoring pass. It was also his 16th career game with 300 yards and four passing TDs, tying Dan Marino for the most in league history.

Manning owns the NFL record with 67 games with 300 or more passing yards. Brees has 62. Also, Manning engineered his 47th career game-winning drive in the fourth quarter two weeks ago when he led Denver to a 35-24 win at San Diego after the Broncos trailed 24-0. That tied Marino for most career fourth-quarter comebacks since 1970.

No lead should be safe tonight.

The franchises have not met since 2008 and that one was an offensive show with Denver winning, 34-32.

Game of the day

Saints (2-4) at Broncos (3-3)

TV: Ch. 2, 8:20 p.m.

The line: Broncos (-6)

The scoop: Easily the best and most interesting game on schedule matching Brees and Manning. ... Broncos coming off a bye after rallying from 24-0 to win at San Diego. Brees threw four TDs in first half as Saints hung on for 35-28 win at Tampa Bay. Interim head coach Joe Vitt comes off suspension to guide Saints.

Outlook: Manning should have fun carving up Saints’ pass defense, which gave up 415 yards to Bucs’ Josh Freeman last week. Denver, 42-35.

Top attractions

Dolphins (3-3) at Jets (3-4)

TV: Ch. 4, 1 p.m.

The line: Jets (-2)

The scoop: Miami, which is improving week by week, had bye to get ready for this one while Jets were going all-in in an OT loss at New England. ... Rookie QB Ryan Tannehill of Fish is cutting down mistakes even though his TD-INT ratio is only 4-6. ... Rex Ryan is only 3-4 against Miami as Jets coach. Anybody seen Tim Tebow?

Outlook: Jets used up energy in Foxborough, Fish coming on. Miami, 24-17.

Giants (5-2) at Cowboys (3-3)

TV: Ch. 29, 4:25 p.m.

The line: Giants (-2)

The scoop: If Eli Manning hadn’t thrown bomb to Victor Cruz with 1:13 left to beat Redskins last week, Cowboys would be playing for first place today. ... Seems strange to have finale of season series between NFC East rivals over this early. Cowboys won at MetLife, 24-17, in season opener and have been unimpressive since. ... Giants giving up 379.7 yards a game. Uncharacteristic.

Outlook: Cowboys just not cutting it. Giants, 20-13.

Falcons (6-0) at Eagles (3-3)

Kickoff: 1 p.m.

The line: Eagles (-3)

The scoop: Each team is coming off bye in rare bit of fair NFL scheduling. How can Atlanta, NFL’s only unbeaten team, be a slight underdog on road? Looks like not everybody is convinced Falcons are real deal after they barely squeaked by Redskins and Raiders in last two. ... Eagles used bye to adjust to new defensive coordinator Todd Bowles.

Outlook: Falcons are coasting while Eagles and Andy Reid are getting desperate. Michael Vick haunts old team, 30-27.

Redskins (3-4) at Steelers (3-3)

TV: Ch. 29, 1 p.m.

The line: Steelers (-4½)

The scoop: Pittsburgh has to rely on third and fourth-string running backs, but still got past disappointing Bengals on the road Sunday night. Now Steelers get to deal with NFL’s best and most dangerous rookie QB, Robert Griffin III, who leads league with 70.4 completion percentage and has rushed for 468 yards and six rushing TDs, second best in league. He had Giants beat last week before Jim Haslett’s defense went to sleep.

Outlook: Redskins top NFL list of over-achieving teams. Pittsburgh, 20-19.

Best of the rest

Panthers (1-5) at Bears (5-1)

Kickoff: 1 p.m.

The line: Bears (-7½)

The scoop: Carolina shakeup began this week with firing of GM Marty Hurney. Panthers have lost last four since upset over Saints in Week Two. ... Bears feasting on turnovers. They lead league with plus-13, but you can’t count on that all the time. Chicago has won last four since losing at Green Bay.

Outlook: Cam Newton of Panthers making just enough mistakes to lose games and Bears live on that. Chicago, 20-10.

Chargers (3-3) at Browns (1-6)

Kickoff: 1 p.m.

The line: Chargers (-3)

The scoop: San Diego coming off bye after blowing leads and losing previous two games. ... Browns rookie QB Brandon Weeden has some impressive numbers but can’t get team to end zone often enough. Rib injury to rookie RB Trent Richardson not helping punchless offense either.

Outlook: Chargers aren’t great road team – or home team for that matter – but Brownies can’t keep up point pace. San Diego, 27-13.

Seahawks (4-3) at Lions (2-4)

Kickoff: 1 p.m.

The line: Lions (-2)

The scoop: Bloom is off the rose for Detroit coach Jim Schwartz. Lions are underachieving and looking more like the bumbling Lions we’ve known (10 straight losing seasons before 2011). Red zone failures cost chance for upset at Chicago on Monday night, a game Detroit needed badly to stay in NFC North race. ... Seattle’s tough defense nearly produced upset at San Francisco but S-Hawks had no TDs and reached red zone only once.

Outlook: Seahawks will find Detroit defense a lot softer than Niners. Seattle, 20-17.

Patriots (4-3) vs. Rams (3-4)

Kickoff: 1 p.m.

The line: Patriots (-7)

The scoop: This one is in London’s Wembley Stadium, then Pats get bye week to prepare for home game against Bills. ... Patriots lead league in total offense (436.1), Tom Brady is tops in passing yards (2,104) and Wes Welker leads with 54 receptions and 688 receiving yards.

Outlook: Rams are dead ducks unless their pass rushers bother Brady. Patriots, 33-20.

Colts (3-3) at Titans (3-4)

Kickoff: 1 p.m.

The line: Titans (-3½)

The scoop: Tennessee is 2-1 at home with wins over Lions and Steelers. Titans RB Chris Johnson had 195 yards, 2 TDs in win over Bills. He had 301 yards and no TDs against other six opponents. Supposedly soft Colts are allowing only 96.5 yards on the ground. Bills would like to be that soft.

Outlook: Andrew Luck impressive, but is 0-2 on road. As Bills learned, Titans have offensive weapons. Tennessee, 30-24.

49ers (5-2) at Cardinals (4-3)

TV: ESPN, Monday, 8:30 p.m.

The line: 49ers (-7)

The scoop: Niners put together just enough offense and kept Seattle out of end zone for 13-6 win in last game after getting humbled at home by Giants. ... Cards had chance for upset at Minnesota, but punted four times, missed field goal, lost a fumble and turned it over on downs twice in trips to Vikings’ territory.

Outlook: Ineffective Cards’ offense won’t get it done. San Francisco, 17-9.

Jaguars (1-5) at Packers (4-3)

Kickoff: 1 p.m.

The line: Packers (-15)

The scoop: Jags had 20-3 lead in third quarter at Oakland last week, managed only one first down the rest of the way and lost in OT. Mike Mularkey has constructed the worst offense in the NFL (235.8-yard average worst in league) and will not have Maurice Jones-Drew for this one. ... Aaron Rodgers of Packers leads league with 19 TD passes and 109.6 passer rating, and he is just warming up.

Outlook: Jaguars look like Buffalo Bills South. Green Bay, 35-10.

Dog of the day

Raiders (2-4) at Chiefs (1-5)

Kickoff: 4:05 p.m.

The line: Chiefs (-1½)

The scoop: How can Raiders travel to Atlanta and get near upset, then go home and need late score and OT field goal to get by woeful Jaguars? Oakland looking for sixth straight win at Arrowhead against old rivals today. ... Brady Quinn starts at QB for Chiefs, who were embarrassed at Tampa Bay two weeks ago. K.C. leads league in rushing average (164.0).

Outlook: Chiefs fans ready to fire everybody but get some consolation. Kansas City, 20-17.

Last week’s results: 9-3 outright, 7-5 versus spread. Season’s record: 52-45 outright, 39-56-3 versus spread.

email: mnorthrop@buffnews.com