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Fire of undetermined origin caused an estimated $150,000 damage Monday afternoon to a four-story brick building at 106 Elmwood Avenue. and $50,000 damage to its contents, according to the Fire Department.

The Red Cross is helping two adult residents of the building with living conditions.

The Fire Department was called to the scene of the smoky fire at 5:05 p.m. and crews were clearing up there just before 6:30 p.m. The cause of the fire remains under investigation.