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The vast expanse of the cosmos and the microscopic machinations of human cells will share wall space in a new exhibition featuring work by Buffalo painter David Mann opening this weekend in Nina Freudenheim Gallery.

Frequent visitors to Freudenheim’s gallery in the Lenox Hotel on North Street are familiar with these far-reaching concerns, having seen recent exhibitions by the likes of Buffalo painter Peter Stephens and others preoccupied with humans’ place in the universe.

Mann’s meticulously rendered acrylic paintings are deliberately constructed to be read as images of cells or molecules or visions of distant galaxies.

“The suggestion of something so small, like cells, is juxtaposed with large scale dimensions, which gives the work a more mystical, rather than methodical quality,” according to a statement from the gallery. “Mann’s work references microbiological and astronomical imagery in an abstract context. Between glowing orbs, some exploding, some imploding, some emerging and some disappearing, vast networks organize the space within the paintings while hinting at natural human social constructs such as families, friendships, and communities.” Colin Dabkowski

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“David Mann: New Paintings”When: 6 p.m. Saturday through June 7. Where: Nina Freudenheim Gallery, 140 North St. Admission: Free. Info: 882-5777 or ninafreudenheimgallery.org.