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A computer problem grounded American Airlines flights across the country for several hours Tuesday afternoon, canceling two flights and delaying others at Buffalo Niagara International Airport.

The systemwide outage, which caused cancellation of more than 750 American and American Eagle flights across the nation, started around midday and lasted until about 4:30 p.m.

In Buffalo, where American flies 50-seat aircraft back and forth from O’Hare International Airport in Chicago, one departing flight and one arriving flight were canceled, according to C. Douglas Hartmayer, spokesman for the Niagara Frontier Transportation Authority.

Hartmayer noted that two evening arrivals and one departure were delayed.

“Customer-wise, the impact was not that great,” Hartmayer said.

American said the computer problem prevented it from accessing Sabre, its reservations system. In addition to reservations, the system handles a multitude of other functions, including printing boarding passes, online check-ins, ticketing and tracking baggage.

The cause was not immediately identified, but American said it was not related to the bombings Monday at the Boston Marathon. Other airlines using Sabre reported that they had no problems.

American officials said they would waive fees for passengers who wanted to change their reservations Tuesday and give refunds to those who decided to cancel their flights.

email: danderson@buffnews.com and rmccarthy@buffnews.com