Two adults and four children were left homeless Saturday afternoon following a house fire on Highgate Avenue.

Buffalo firefighters responded to a call at 468 Highgate shortly after 3:30 p.m., fire officials said. The blaze, which started on the second floor of the 1½-story dwelling, caused $30,000 damage to the building and $15,000 damage to the contents. The Red Cross is assisting the family.