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Dear Mayo Clinic: Can probiotics really help prevent a cold? What about vitamin C? Answer: When you’re trying to keep a cold at bay, there’s no shortage of self-help suggestions out there. The two you mention – probiotics and vitamin C – are common ideas. Evidence does exist that shows probiotics can help boost your immune system and may ward off some colds. With vitamin C, there is more hype than reality. There’s no clear evidence vitamin C makes a difference, and taking too much vitamin C could lead to some gastrointestinal side effects.

The common cold is caused by a virus that infects your nose and throat. The infection leads to the runny nose, sore throat, congestion, watery eyes, sneezing and other familiar symptoms people often experience with a cold. More than 100 viruses can cause a common cold. That explains why the signs and symptoms can vary a bit from one cold to the next.

Probiotics are a type of “good” bacteria found in yogurt. They also are available in some over-the-counter supplements. Taking probiotics has long been touted as a way to boost the immune system and keep people healthy.

Over the past several decades, numerous research studies have looked into that claim. Findings from those studies have shown that probiotics do, in fact, appear to improve the body’s immune response. That in turn helps the body be better prepared to fight off certain infections, including the common cold.

That doesn’t mean if you eat yogurt you will never have a cold. But taking probiotics regularly can lower your chances of getting a cold. And, if you do catch a cold, probiotics may help reduce the severity of your symptoms and shorten how long they last.

Of course, there are plenty of other steps you can take to help keep from catching a cold that don’t involve taking anything. Wash your hands regularly, keep kitchen and bathroom surfaces clean, and don’t share drinking glasses or utensils with others. Using alcohol hand sanitizers is an excellent way to keep hands clean while on the move.